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Article

Comparative analysis of Clostridium difficile clinical isolates belonging to different genetic lineages and time periods.

Journal of medical microbiology - 1 Nov 2004

Spigaglia Patrizia, Mastrantonio Paola

Abstract excerpt

Recent studies have shown that Clostridium difficile strains with variant toxins and those with resistance to macrolide-lincosamide-streptogramin B (MLSB) are increasingly causing severe disease and outbreaks in hospital settings. Here, the pathogenicity locus (PaLoc), the acquisition of binary toxin, and the genotypic and phenotypic characteristics of antibiotic resistance of 74 C. difficile clinical strains...

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Identifiers

PMID: 15496392
DOI: 10.1099/jmm.0.45682-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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