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Article

Cutting edge: identification of hepatitis C virus-specific CD8+ T cells restricted by donor HLA alleles following liver transplantation.

Journal of immunology (Baltimore, Md. : 1950) - 1 Nov 2004

Rosen Hugo R, Hinrichs David J, Leistikow Rachel L, Callender Glenda, Wertheimer Anne M, Nishimura Michael I, Lewinsohn David M

Abstract excerpt

By necessity, human liver transplantation is performed across HLA barriers. As a result, intracellular infection of the allograft presents a unique immunologic challenge for the recipient's immune system. In this study, we describe the presence of HLA-A2-restricted, hepatitis C virus (HCV)-specific CD8+ T cells in liver transplant recipients in whom the allograft is HLA-A2 positive and the recipient is HLA-A2...

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Source

Identifiers

PMID: 15494481
DOI: 10.4049/jimmunol.173.9.5355

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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