Article
Association of angiotensin II type 1 receptor gene polymorphism with essential hypertension.
Chinese medical journal - 1 Dec 2001
Jiang Z, Zhao W, Yu F, Xu G
Abstract excerpt
OBJECTIVE: To determine whether the polymorphism A1166C in the angiotensin II type 1 receptor (AT1R) gene is associated with essential hypertension. METHODS: A case-control study was carried out using 125 hypertensive and 103 normotensive subjects. The A-->C variant at position 1166 (A1166C) of the AT1R gene was identified by polymerase chain reaction (PCR) and PCR/restriction fragment length polymorphism...
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