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Article

Actin-mediated delivery of astral microtubules instructs Kar9p asymmetric loading to the bud-ward spindle pole.

Molecular biology of the cell - 1 Aug 2010

Cepeda-García Cristina, Delgehyr Nathalie, Juanes Ortiz M Angeles, ten Hoopen Rogier, Zhiteneva Alisa, Segal Marisa

Abstract excerpt

In Saccharomyces cerevisiae, Kar9p, one player in spindle alignment, guides the bud-ward spindle pole by linking astral microtubule plus ends to Myo2p-based transport along actin cables generated by the formins Bni1p and Bnr1p and the polarity determinant Bud6p. Initially, Kar9p labels both poles but progressively singles out the bud-ward pole. Here, we show that this polarization requires cell polarity...

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Identifiers

PMID: 20534809
DOI: 10.1091/mbc.e10-03-0197
PMCID: PMC2912354

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Actin-mediated delivery of astral microtubules instructs Kar9p asymmetric loading to the bud-ward spindle pole.PMID 20534809Read ↗

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