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Article

Kar9 symmetry breaking alone is insufficient to ensure spindle alignment.

Scientific reports - 19 Feb 2021

Meziane Miram, Genthial Rachel, Vogel Jackie

Abstract excerpt

Spindle positioning must be tightly regulated to ensure asymmetric cell divisions are successful. In budding yeast, spindle positioning is mediated by the asymmetric localization of microtubule + end tracking protein Kar9. Kar9 asymmetry is believed to be essential for spindle alignment. However, the temporal correlation between symmetry breaking and spindle alignment has not been measured. Here, we establish a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33608583
DOI: 10.1038/s41598-021-83136-w
PMCID: PMC7895971

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