Article
Mutation of l7Rn3 shows that Odz4 is required for mouse gastrulation.
Genetics - 1 Jan 2005
Lossie Amy C, Nakamura Hisashi, Thomas Sharon E, Justice Monica J
Abstract excerpt
A mouse homolog of the Drosophila pair-rule gene Odd Oz (Odz4) maps to the critical region of the l7Rn3 locus on mouse chromosome 7. Here we show that Odz4 is an excellent candidate for this allelic series because (1) it spans the entire critical region, (2) the phenotypes correlate with embryonic expression, (3) the complex genetic inheritance of the alleles is consistent with complex transcriptional regulation,...
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