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Article

Dnm3os, a non-coding RNA, is required for normal growth and skeletal development in mice.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Dec 2008

Watanabe Tokumitsu, Sato Takahiro, Amano Tomokazu, Kawamura Yumiko, Kawamura Naohiro, Kawaguchi Hiroshi, Yamashita Naohide, Kurihara Hiroki, Nakaoka Takashi

Abstract excerpt

Dnm3os, a gene that is transcribed into a non-coding RNA (ncRNA), contains three micro RNAs (miRNAs), miR-199a, miR-199a*, and miR-214, whose functions remain unknown in mammals. In this study, we introduced the lacZ gene into the Dnm3os locus to recapitulate its expression pattern and disrupt its function. Dnm3os(+/lacZ) heterozygous embryos showed beta-galactosidase activity, which reflected the authentic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18985749
DOI: 10.1002/dvdy.21787

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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