Article
The MDR1 3435 polymorphism in patients with rheumatoid arthritis.
International journal of clinical pharmacology and therapeutics - 1 Sept 2004
Pawlik A, Wrzesniewska J, Fiedorowicz-Fabrycy I, Gawronska-Szklarz B
Abstract excerpt
OBJECTIVE: Rheumatoid arthritis (RA) is a multifactorial disease, the pathogenesis of which involves immunological, genetic and environmental factors. P-glycoprotein (P-gp) encoded by the MDR1 gene, is an important transporter for many drugs, xenobiotics and cytokines and may be associated with m...
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