Article
Thermo-osmoregulation of heat-labile enterotoxin expression by Escherichia coli.
Current microbiology - 1 Nov 2004
Trachman Julie D, Yasmin Munira
Abstract excerpt
Enterotoxigenic Escherichia coli causes diarrhea by producing several virulence factors including heat-labile enterotoxin (LT). LT is maximally expressed at 37 degrees C. The histone-like nucleoid structuring protein (H-NS) appears to inhibit LT expression by binding to a downstream regulatory element (DRE) at low temperatures. An hns+ E. coli strain, X7026, carrying an LT-beta-galactosidase translational fusion...
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