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Ler of pathogenic Escherichia coli forms toroidal protein–DNA complexes

7 Jan 2011

Abstract excerpt

Enteropathogenic and enterohaemorrhagic Escherichia coli are related pathotypes of bacteria that cause acute watery diarrhoea and haemorrhagic colitis, respectively, and enterohaemorrhagic E. coli can lead to a serious complication known as haemolytic uraemic syndrome. In both bacteria the global regulatory protein Ler controls virulence. The ler gene is found within the locus of enterocyte effacement, or LEE,...

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PMID: 21212119
DOI: 10.1099/mic.0.046094-0

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Ler of pathogenic Escherichia coli forms toroidal protein–DNA complexesPMID 21212119Read ↗

Interaction of Ler at the LEE5 ( tir ) Operon of Enteropathogenic Escherichia coliSemantic proximity Read ↗

Bacterial-Chromatin Structural Proteins Regulate the Bimodal Expression of the Locus of Enterocyte Effacement (LEE) Pathogenicity Island in Enteropathogenic Escherichia coliSemantic proximity Read ↗

Mutational analysis of the locus of enterocyte effacement-encoded regulator (Ler) of enteropathogenic Escherichia coli.Semantic proximity Read ↗

H-NST induces LEE expression and the formation of attaching and effacing lesions in enterohemorrhagic Escherichia coli.Semantic proximity Read ↗

Ler interdomain linker is essential for anti-silencing activity in enteropathogenic Escherichia coli.Semantic proximity Read ↗

A truncated H-NS-like protein from enteropathogenic Escherichia coli acts as an H-NS antagonist.Semantic proximity Read ↗

Activation of enteropathogenic <i>Escherichia coli</i> (EPEC) <i>LEE2</i> and <i>LEE3</i> operons by LerSemantic proximity Read ↗

Characterisation and identification of binding partners of non-LEE-encoded protein H of enteropathogenic E. coliSemantic proximity Read ↗

A Positive Regulatory Loop Controls Expression of the Locus of Enterocyte Effacement-Encoded Regulators Ler and GrlASemantic proximity Read ↗

Identification of a negative regulator for the pathogenicity island of enterohemorrhagic Escherichia coli O157:H7.Semantic proximity Read ↗

SOS regulation of the type III secretion system of enteropathogenic Escherichia coli.Semantic proximity Read ↗

Systematic mutational analysis revealing the functional domain organization of Escherichia coli nucleoid protein H-NS.Semantic proximity Read ↗

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