Article
Thermoregulated expression of virulence genes in enteropathogenic Escherichia coli.
Microbiology (Reading, England) - 1 Sept 2002
Umanski Tatiana, Rosenshine Ilan, Friedberg Devorah
Abstract excerpt
Enteropathogenic Escherichia coli (EPEC) causes severe diarrhoea in young children. The locus of enterocyte effacement (LEE) pathogenicity island comprises a cluster of operons encoding a type III secretion system and related proteins that are associated with EPEC virulence. The LEE1 operon encodes Ler that positively regulates the LEE2, LEE3, LEE4, LEE5 and espG transcriptional units. The LEE operons are...
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