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Article

SNT-2 interacts with ERK2 and negatively regulates ERK2 signaling in response to EGF stimulation.

Biochemical and biophysical research communications - 19 Nov 2004

Huang Lin, Gotoh Noriko, Zhang Shengliang, Shibuya Masabumi, Yamamoto Tadashi, Tsuchida Nobuo

Abstract excerpt

The control of cellular responses with fibroblast growth factors and neurotrophins is mediated through membrane-linked docking proteins, SNT (suc1-binding neurotrophic target)-1/FRS2alpha and SNT-2/FRS2beta. ERK1/2 are members of the mitogen-activated protein kinase family that regulate diverse cellular activities in response to various stimuli. Here, we demonstrate that SNT-2 does not become tyrosine...

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Source

Identifiers

PMID: 15485655
DOI: 10.1016/j.bbrc.2004.09.152

Genes

EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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