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Article

Structure of a glutamate transporter homologue from Pyrococcus horikoshii.

Nature - 14 Oct 2004

Yernool Dinesh, Boudker Olga, Jin Yan, Gouaux Eric

Abstract excerpt

Glutamate transporters are integral membrane proteins that catalyse the concentrative uptake of glutamate from the synapse to intracellular spaces by harnessing pre-existing ion gradients. In the central nervous system glutamate transporters are essential for normal development and function, and are implicated in stroke, epilepsy and neurodegenerative diseases. Here we present the crystal structure of a...

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PMID: 15483603
DOI: 10.1038/nature03018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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