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Article

Phosphatidylinositol 3-kinase/Akt-dependent and -independent protection against apoptosis in normal human melanocytes.

The Journal of investigative dermatology - 1 Nov 2004

Oka Masahiro, Kageyama Akiko, Fukunaga Mizuho, Bito Toshinori, Nagai Hiroshi, Nishigori Chikako

Abstract excerpt

Normal human melanocytes require the synergistic action of several growth-promoting agents for their growth in serum-free medium. The ability of four representative growth promoting agents including insulin, 12-O-tetradecanoylphorbol-13-acetate (TPA), basic fibroblast growth factor (bFGF), and 3-isobutyl-1-methylxanthine (IBMX), (iTbI) to protect melanocytes against apoptosis was examined. Also, the involvement...

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Identifiers

PMID: 15482482
DOI: 10.1111/j.0022-202X.2004.23454.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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