Article
Role of Akt in growth and survival of PANC-1 pancreatic cancer cells.
Pancreas - 1 Jan 2002
Yao Zan, Okabayashi Yoshinori, Yutsudo Yoshihiro, Kitamura Tadahiro, Ogawa Wataru, Kasuga Masato
Abstract excerpt
INTRODUCTION: Akt is involved in different cellular processes such as cell growth, cell differentiation, and anti-apoptosis. AIMS: To investigate the role of Akt in cell growth and survival in PANC-1 pancreatic cancer cells. METHODOLOGY AND RESULTS: Insulin-like growth factor (IGF)-I induced Akt activation in a dose-dependent manner and stimulated anchorage-dependent and anchorage-independent cell growth of...
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