Article
Use of unphased multilocus genotype data in indirect association studies.
Genetic epidemiology - 1 Dec 2004
Clayton David, Chapman Juliet, Cooper Jason
Abstract excerpt
It is usually assumed that detection of a disease susceptability gene via marker polymorphisms in linkage disequilibrium with it is facilitated by consideration of marker haplotypes. However, capture of the marker haplotype information requires resolution of gametic phase, and this must usually b...
Topics
- Genetic Markers
- Genetic Predisposition to Disease
- Genetics, Population
- Genotype
- Haplotypes
- Humans
- Linkage Disequilibrium
- Models, Genetic
- Models, Statistical