Article
Use of unphased multilocus genotype data in indirect association studies.
Genetic epidemiology - 1 Dec 2004
Clayton David, Chapman Juliet, Cooper Jason
Abstract excerpt
It is usually assumed that detection of a disease susceptability gene via marker polymorphisms in linkage disequilibrium with it is facilitated by consideration of marker haplotypes. However, capture of the marker haplotype information requires resolution of gametic phase, and this must usually be inferred statistically. Recently, we questioned the value of the marker haplotype information, and suggested that...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
