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Article

PPARdelta status and Apc-mediated tumourigenesis in the mouse intestine.

Oncogene - 25 Nov 2004

Reed Karen R, Sansom Owen J, Hayes Anthony J, Gescher Andreas J, Winton Douglas J, Peters Jeffrey M, Clarke Alan R

Abstract excerpt

Based on recent reports that peroxisome proliferator-activated receptor delta (PPARdelta) activation promotes tumourigenesis, we have investigated the role of this protein in Apc-mediated intestinal tumourigenesis. We demonstrate that the inactivation of Apc in the adult small intestine, while ca...

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Source

Identifiers

PMID: 15480419
DOI: 10.1038/sj.onc.1208143

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15480419-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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