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Article

Peroxisome proliferator-activated receptor-delta attenuates colon carcinogenesis.

Nature medicine - 1 May 2004

Harman Fred S, Nicol Christopher J, Marin Holly E, Ward Jerrold M, Gonzalez Frank J, Peters Jeffrey M

Abstract excerpt

Peroxisome proliferator-activated receptor-delta (PPAR-delta; also known as PPAR-beta) is expressed at high levels in colon tumors, but its contribution to colon cancer is unclear. We examined the role of PPAR-delta in colon carcinogenesis using PPAR-delta-deficient (Ppard(-/-)) mice. In both the...

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PMID: 15048110
DOI: 10.1038/nm1026

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15048110-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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