Article
RNA polymerase I remains intact without subunit exchange through multiple rounds of transcription in Saccharomyces cerevisiae.
Proceedings of the National Academy of Sciences of the United States of America - 19 Oct 2004
Schneider David A, Nomura Masayasu
Abstract excerpt
Previous experiments using mammalian cells suggested that after each round of transcription, RNA polymerase I (Pol I) dissociates into subunits that leave and reenter the nucleolus as individual subunits, before formation of a new initiation complex. In this study, we show that the size and subunit composition of Pol I did not change significantly when Pol I was not engaged in rRNA transcription, brought about by...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
