Article
Congenital hydrocephalus in genetically engineered mice.
Veterinary pathology - 1 Jan 2012
Vogel P, Read R W, Hansen G M, Payne B J, Small D, Sands A T, Zambrowicz B P
Abstract excerpt
There is evidence that genetic factors play a role in the complex multifactorial pathogenesis of hydrocephalus. Identification of the genes involved in the development of this neurologic disorder in animal models may elucidate factors responsible for the excessive accumulation of cerebrospinal fluid in hydrocephalic humans. The authors report here a brief summary of findings from 12 lines of genetically...
Topics
- Animals
- Brain
- Cerebellum
- Developmental Disabilities
- Disease Models, Animal
- Genetic Engineering
- Humans
- Hydrocephalus
- Infertility
- Mice
- Mice, Knockout
- Mice, Transgenic