Article
CCR2 genotype and disease progression in a treated population of HIV type 1-infected women.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 15 Sept 2004
Philpott Sean, Burger Harold, Tarwater Patrick M, Lu Ming, Gange Stephen J, Anastos Kathryn, Cohen Mardge, Greenblatt Ruth M, Kovacs Andrea, Minkoff Howard, Young Mary, Miotti Paolo, Dupuis Michelle, Weiser Barbara
Abstract excerpt
Both antiretroviral therapy and the human coreceptor polymorphism CCR2-V64I slow progression of human immunodeficiency virus type 1 (HIV-1) disease. To examine the effect of V64I on disease progression in patients receiving therapy, we determined CCR2 genotypes in the Women's Interagency HIV Study cohort. We studied 2047 HIV-1-infected women, most of whom initiated treatment during the study. No association was...
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