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Article

The Drosophila TRPP cation channel, PKD2 and Dmel/Ced-12 act in genetically distinct pathways during apoptotic cell clearance.

PloS one - 1 Jan 2012

Van Goethem Emeline, Silva Elizabeth A, Xiao Hui, Franc Nathalie C

Abstract excerpt

Apoptosis, a genetically programmed cell death, allows for homeostasis and tissue remodelling during development of all multi-cellular organisms. Phagocytes swiftly recognize, engulf and digest apoptotic cells. Yet, to date the molecular mechanisms underlying this phagocytic process are still poorly understood. To delineate the molecular mechanisms of apoptotic cell clearance in Drosophila, we have carried out a...

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Identifiers

PMID: 22347485
DOI: 10.1371/journal.pone.0031488
PMCID: PMC3275576

Genes

PKD2

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