Article
SNPs on chromosome 5p15.3 associated with myocardial infarction in Japanese population.
Journal of human genetics - 1 Jan 2011
Aoki Asako, Ozaki Kouichi, Sato Hiroshi, Takahashi Atsushi, Kubo Michiaki, Sakata Yasuhiko, Onouchi Yoshihiro, Kawaguchi Takahisa, Lin Tsung-Hsien, Takano Hitoshi, Yasutake Masahiro, Hsu Po-Chao, Ikegawa Shiro, Kamatani Naoyuki, Tsunoda Tatsuhiko, Juo Suh-Hang H, Hori Masatsugu, Komuro Issei, Mizuno Kyoichi, Nakamura Yusuke, Tanaka Toshihiro
Abstract excerpt
Myocardial infarction (MI) occurs as the result of complex interactions of multiple genetic and environmental factors. By conducting a genome wide association study in a Japanese population using 210,785 single nucleotide polymorphism (SNP) markers, we identified a novel susceptible locus for MI on chromosome 5p15.3. An SNP (rs11748327) in this locus showed significant association in several independent cohorts...
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