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Article

Inactivating mutations of the Siah-1 gene in gastric cancer.

Oncogene - 11 Nov 2004

Kim Chang Jae, Cho Yong Gu, Park Cho Hyun, Jeong Seong Whan, Nam Suk Woo, Kim Su Young, Lee Sug Hyung, Yoo Nam Jin, Lee Jung Young, Park Won Sang

Abstract excerpt

SIAH-1: is the mammalian homolog of Drosophila seven in absentia (sina) and has been identified as a p53-inducible gene. Siah-1 can induce cell cycle arrests, tumor suppression, and apoptosis through a novel beta-catenin degradation pathway. To determine whether genetic alterations of Siah-1 gene...

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Source

Identifiers

PMID: 15467739
DOI: 10.1038/sj.onc.1208113

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15467739-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Inactivating mutations of the Siah-1 gene in gastric cancer.PMID 15467739Read ↗

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