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Article

Reduced expression of RAS protein activator like-1 in gastric cancer.

International journal of cancer - 15 Mar 2011

Seto Motoko, Ohta Miki, Ikenoue Tsuneo, Sugimoto Takafumi, Asaoka Yoshinari, Tada Motohisa, Mohri Dai, Kudo Yotaro, Ijichi Hideaki, Tateishi Keisuke, Otsuka Motoyuki, Hirata Yoshihiro, Maeda Shin, Koike Kazuhiko, Omata Masao

Abstract excerpt

RAS signaling is frequently deregulated in human neoplasms. However, RAS mutations have been found in only a small proportion of human gastric cancers, implicating other mechanisms in the activation of RAS signaling in gastric tumorigenesis. We have previously reported that decreased expression of RAS protein activator like-1 (RASAL1), a member of the RAS-GTPase-activating proteins that switch off RAS activity,...

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Share to Epigenesis, Genetic
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20473946
DOI: 10.1002/ijc.25459

Genes

RASAL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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