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Article

Immunoregulatory effects of regulated, lung-targeted expression of IL-10 in vivo.

American journal of physiology. Lung cellular and molecular physiology - 1 Feb 2005

Spight Donn, Zhao Bin, Haas Michael, Wert Susan, Denenberg Alvin, Shanley Thomas P

Abstract excerpt

Regulation of pulmonary inflammation involves an intricate balance of both pro- and anti-inflammatory mediators. Acute lung injury can result from direct pulmonary insults that activate alveolar macrophages to respond with increased cytokine expression. Such cytokine gene expression is mediated i...

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Identifiers

PMID: 15466252
DOI: 10.1152/ajplung.00122.2004

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15466252-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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