Article
Respiratory epithelial cells regulate lung inflammation in response to inhaled endotoxin.
American journal of physiology. Lung cellular and molecular physiology - 1 Jul 2004
Skerrett Shawn J, Liggitt H Denny, Hajjar Adeline M, Ernst Robert K, Miller Samuel I, Wilson Christopher B
Abstract excerpt
To determine the role of respiratory epithelial cells in the inflammatory response to inhaled endotoxin, we selectively inhibited NF-kappa B activation in the respiratory epithelium using a mutant I kappa B-alpha construct that functioned as a dominant negative inhibitor of NF-kappa B translocati...
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