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Article

Interleukin 10 overexpression alters survival in the setting of gram-negative pneumonia following lung contusion.

Shock (Augusta, Ga.) - 1 Apr 2014

Dolgachev Vladislav A, Yu Bi, Sun Lei, Shanley Thomas P, Raghavendran Krishnan, Hemmila Mark R

Abstract excerpt

OBJECTIVE: Lung contusion injury produces a vulnerable window within the inflammatory defenses of the lung that predisposes the patient to pneumonia. Interleukin 10 (IL-10) is a known anti-inflammatory mediator produced by macrophages and capable of downregulating acute lung inflammation. We investigated the impact of increased levels of IL-10 within the lung on survival and the host response to trauma in the...

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Source

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Identifiers

PMID: 24430542
DOI: 10.1097/SHK.0000000000000123
PMCID: PMC4019007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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