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Article

Novel APC gene mutations associated with protein alteration in diffuse type gastric cancer.

BMC medical genetics - 2 Jun 2017

Ghatak Souvik, Chakraborty Payel, Sarkar Sandeep Roy, Chowdhury Biswajit, Bhaumik Arup, Kumar Nachimuthu Senthil

Abstract excerpt

BACKGROUND: The role of adenomatous polyposis coli (APC) gene in mitosis might be critical for regulation of genomic stability and chromosome segregation. APC gene mutations have been associated to have a role in colon cancer and since gastric and colon tumors share some common genetic lesions, it is relevant to investigate the role of APC tumor suppressor gene in gastric cancer. METHODS: We investigated for...

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Source

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Identifiers

PMID: 28576136
DOI: 10.1186/s12881-017-0427-2
PMCID: PMC5457612

Genes

APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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