Article
Does interleukin-6 genotype influence cerebral injury or developmental progress after preterm birth?
Pediatrics - 1 Oct 2004
Harding David R, Dhamrait Sukbhir, Whitelaw Andrew, Humphries Steve E, Marlow Neil, Montgomery Hugh E
Abstract excerpt
OBJECTIVE: The severity of the proinflammatory response may determine outcome in the critically ill. Genetic variation in the promoter region of the gene encoding the proinflammatory cytokine interleukin-6 (IL-6; -174 CC genotype) may encode enhanced production of IL-6. Our objective was to determine whether the CC genotype is associated with worse early illness severity, neurologic injury, and lower...
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