Article
The association between sex-related interleukin-6 gene polymorphisms and the risk for cerebral palsy.
Journal of neuroinflammation - 6 Jun 2014
Bi Dan, Chen Mingjie, Zhang Xiaoli, Wang Honglian, Xia Lei, Shang Qing, Li Tongchuan, Zhu Dengna, Blomgren Klas, He Lin, Wang Xiaoyang, Xing Qinghe, Zhu Changlian
Abstract excerpt
BACKGROUND: The relationship between genetic factors and the development of cerebral palsy (CP) has recently attracted much attention. Polymorphisms in the genes encoding proinflammatory cytokines have been shown to be associated with susceptibility to perinatal brain injury and development of CP. Interleukin-6 (IL-6) is a proinflammatory cytokine that plays a pivotal role in neonatal brain injury, but...
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