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Article

Requirements for DNA unpairing during displacement synthesis by HIV-1 reverse transcriptase.

The Journal of biological chemistry - 17 Dec 2004

Winshell Jamie, Paulson Benjamin A, Buelow Ben D, Champoux James J

Abstract excerpt

DNA displacement synthesis by reverse transcriptase during retroviral replication is required for the production of the linear precursor to integration. The sensitivity of unpaired thymines to KMnO(4) oxidation was used to probe for the extent of DNA melting by human immunodeficiency virus, type...

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Share to Dimerization
Share to DNA Primers
Share to DNA, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Electrophoresis, Polyacrylamide Gel

Share to HIV Reverse Transcriptase

Share to Nucleic Acid Conformation

Share to Oligonucleotides

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Source

Identifiers

PMID: 15465813
DOI: 10.1074/jbc.M409134200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15465813-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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