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Article

Variation in alternative splicing across human tissues.

Genome biology - 1 Jan 2004

Yeo Gene, Holste Dirk, Kreiman Gabriel, Burge Christopher B

Abstract excerpt

BACKGROUND: Alternative pre-mRNA splicing (AS) is widely used by higher eukaryotes to generate different protein isoforms in specific cell or tissue types. To compare AS events across human tissues, we analyzed the splicing patterns of genomically aligned expressed sequence tags (ESTs) derived from libraries of cDNAs from different tissues. RESULTS: Controlling for differences in EST coverage among tissues, we...

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Identifiers

PMID: 15461793
DOI: 10.1186/gb-2004-5-10-r74
PMCID: PMC545594

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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