Article
[Prevalence of the A1555G mutation in the mitochondrial DNA in patients with cochlear or vestibular damage due to aminoglycoside-induced ototoxicity].
Acta otorrinolaringologica espanola - 1 May 2004
Gallo-Terán J, Arellano B, Morales-Angulo C, Modamio-Høybjør S, Moreno-Pelayo M A, Ramírez-Camacho R, del Castillo I, Moreno F
Abstract excerpt
OBJECTIVE: To determine the frequency of the A1555G mutation in the mitochondrial genome among Spanish patients with aminoglycoside-induced ototoxicity. PATIENTS AND METHODS: We screened 25 unrelated cases, totalling 39 individuals with cochlear or vestibular damage due to aminoglycoside-induced ototoxicity. This group was made up of 18 subjects from 4 unrelated families with a history of aminoglycoside...
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