Article
[Large-scale screening of mtDNA A1555G mutation in China and its significance in prevention of aminoglycoside antibiotic induced deafness].
Zhonghua yi xue za zhi - 23 May 2006
Liu Xin, Dai Pu, Huang De-liang, Yuan Hui-jun, Li Wei-min, Cao Ju-yang, Yu Fei, Zhang Rui-ning, Lin Hong-yan, Zhu Xiu-hui, He Yong, Yu You-jun, Yao Kun
Abstract excerpt
OBJECTIVE: To explore the necessity of large-scale screening of mtDNA A1555G mutation in prevention of aminoglycoside antibiotic induced deafness (AAID) and to develop a feasible method to prevent AAID. METHODS: A total of 1836 patients with non-syndromic hearing impairment (NSHI), 1352 students of schools for deaf-mutes in 11 provinces and municipality in China, 413 out-patients, and 71 persons from the families...
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