Article
Acute hepatitis C in HIV-infected patients: rare spontaneous clearance correlates with weak memory CD4 T-cell responses to hepatitis C virus.
AIDS (London, England) - 23 Oct 2009
Schnuriger Aurélie, Dominguez Stéphanie, Guiguet Marguerite, Harfouch Sawsan, Samri Assia, Ouazene Zineb, Slama Laurence, Simon Anne, Valantin Marc-Antoine, Thibault Vincent, Autran Brigitte
Abstract excerpt
OBJECTIVES: To explore the parameters of specific immunity to hepatitis C virus (HCV) associated with virus clearance during acute HCV infection in HIV coinfection. METHODS: HIV-infected patients without prior HCV infection were prospectively enrolled for acute hepatitis C and followed up over 15 months. HCV-specific T cells were assessed by proliferation, ELISpot, intracellular cytokine staining and pentamer...
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