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Mutations and polymorphisms associated with antiretroviral drugs in HIV-1C-infected African patients.

Antiviral chemistry & chemotherapy - 1 Jul 2004

Doualla-Bell Florence, Gaseitsiwe Simane, Ndungú Thumbi, Modukanele Musetsanagepe, Peter Trevor, Novitsky Vladimir, Ndwapi Ndwapi, Tendani Gaolathe, Avalos Ava, Wester William, Bussmann Hermann, Cardiello Peter, Marlink Richard, Moffat Howard, Thior Ibou, Wainberg Mark A, Essex Max

Abstract excerpt

To detect and characterize polymerase gene (pol) polymorphisms and mutation patterns in HIV-1C-infected Batswana patients treated with reverse transcriptase inhibitors, samples from AIDS patients treated with highly active antiretroviral therapy (HAART) were sequenced for the region encompassing the entire HIV-1 protease (PR) and the first 335 amino acids of reverse transcriptase (RT). Amongst the 16 patients...

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Identifiers

PMID: 15457680
DOI: 10.1177/095632020401500402

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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