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Article

hRDH-E2 gene polymorphisms, variable transcriptional start sites, and psoriasis.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Aug 2004

Matsuzaka Yasunari, Okamoto Koichi, Yoshikawa Yoko, Takaki Asumi, Oka Akira, Mabuchi Tomotaka, Iizuka Mariko, Ozawa Akira, Tamiya Gen, Kulski Jerzy K, Inoko Hidetoshi

Abstract excerpt

hRDH-E2 is a member of the short-chain alcohol dehydrogenase/reductase (SDR) family that converts retinol to retinaldehyde as the first and rate-limiting step in the retinoic acid synthetic pathway. This pathway is critical for the maintenance of epidermal homeostasis in vivo. Previously, we reported that the mRNA levels of hRDH-E2 in psoriatic skin were elevated significantly compared with that in healthy...

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Identifiers

PMID: 15457346
DOI: 10.1007/s00335-004-2349-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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