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Article

Five non-synonymous SNPs in the gene encoding human deoxyribonuclease I-like 2 implicated in terminal differentiation of keratinocytes reduce or abolish its activity.

Electrophoresis - 1 Feb 2013

Ueki Misuzu, Fujihara Junko, Kimura-Kataoka Kaori, Takeshita Haruo, Iida Reiko, Yasuda Toshihiro

Abstract excerpt

Several non-synonymous SNPs in the human deoxyribonuclease I-like 2 (DNase 1L2) gene responsible for DNA degradation during terminal differentiation of epidermal keratinocytes have been identified. However, only limited population data are available, and furthermore the effect of these SNPs on the DNase 1L2 activity remains unknown. Genotyping of all of the 17 SNPs was performed using the PCR-RFLP method in three...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 23161465
DOI: 10.1002/elps.201200415

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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