Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A novel locus for pure recessive hereditary spastic paraplegia maps to 10q22.1-10q24.1.

Annals of neurology - 1 Oct 2004

Meijer Inge A, Cossette Patrick, Roussel Julie, Benard Melanie, Toupin Sylvie, Rouleau Guy A

Abstract excerpt

The hereditary spastic paraplegias (HSPs) are a group of clinically and genetically heterogeneous disorders characterized by progressive lower-limb spasticity. In this study, we performed linkage analysis on an autosomal recessive pure HSP family and mapped the disease to chromosome 10q22.1-10q24.1, a locus partially overlapping the existing SPG9 locus. We have either identified a novel locus for pure recessive...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Mapping
Share to Chromosomes, Human, Pair 10

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Family Health

Share to Genes, Recessive

Share to Genetic Linkage

Share to Genetic Markers

Share to Pedigree

Share to Spastic Paraplegia, Hereditary

Source

Identifiers

PMID: 15455396
DOI: 10.1002/ana.20239

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A novel locus for pure recessive hereditary spastic paraplegia maps to 10q22.1-10q24.1.PMID 15455396Read ↗

A new locus for autosomal dominant "pure" hereditary spastic paraplegia mapping to chromosome 12q13, and evidence for further genetic heterogeneity.Semantic proximity Read ↗

A new locus for autosomal dominant pure spastic paraplegia, on chromosome 2q24-q34.Semantic proximity Read ↗

Autosomal dominant spastic paraplegia: refined SPG8 locus and additional genetic heterogeneity.Semantic proximity Read ↗

A novel locus for an autosomal recessive hereditary spastic paraplegia (SPG35) maps to 16q21-q23.Semantic proximity Read ↗

JASPAC: Japan Spastic Paraplegia Research ConsortiumSemantic proximity Read ↗

Autosomal recessive spastic paraplegia (SPG30) with mild ataxia and sensory neuropathy maps to chromosome 2q37.3.Semantic proximity Read ↗

A new phenotype linked to SPG27 and refinement of the critical region on chromosome.Semantic proximity Read ↗

A SPAST gene-related hereditary spastic paraplegia type 4 family: Identification by a novel mutationSemantic proximity Read ↗

Autosomal dominant spastic paraplegia with peripheral neuropathy maps to chr12q23-24.Semantic proximity Read ↗

Recent advances in hereditary spastic paraplegia.Semantic proximity Read ↗

Autosomal recessive spastic paraplegia (SPG45) with mental retardation maps to 10q24.3-q25.1.Semantic proximity Read ↗

Fine mapping and genetic heterogeneity in the pure form of autosomal dominant familial spastic paraplegia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.