Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Autosomal recessive spastic paraplegia (SPG30) with mild ataxia and sensory neuropathy maps to chromosome 2q37.3.

Brain : a journal of neurology - 1 Jun 2006

Klebe Stephan, Azzedine Hamid, Durr Alexandra, Bastien Patrick, Bouslam Naima, Elleuch Nizar, Forlani Sylvie, Charon Celine, Koenig Michel, Melki Judith, Brice Alexis, Stevanin Giovanni

Abstract excerpt

The hereditary spastic paraplegias (HSPs) are a clinically and genetically heterogeneous group of neurodegenerative diseases characterized by progressive spasticity in the lower limbs. Twenty-nine different loci (SPG) have been mapped so far, and 11 responsible genes have been identified. Clinically, one distinguishes between pure and complex HSP forms which are variably associated with numerous combinations of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cerebellar Ataxia
Share to Chromosomes, Human, Pair 2

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Consanguinity

Share to Genes, Recessive

Share to Hereditary Sensory and Autonomic Neuropathies

Share to Lod Score

Share to Neural Conduction

Share to Spastic Paraplegia, Hereditary

Source

Identifiers

PMID: 16434418
DOI: 10.1093/brain/awl012

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Autosomal recessive spastic paraplegia (SPG30) with mild ataxia and sensory neuropathy maps to chromosome 2q37.3.PMID 16434418Read ↗

A new phenotype linked to SPG27 and refinement of the critical region on chromosome.Semantic proximity Read ↗

Spastic paraplegia 5: Locus refinement, candidate gene analysis and clinical description.Semantic proximity Read ↗

Tunisian hereditary spastic paraplegias: clinical variability supported by genetic heterogeneity.Semantic proximity Read ↗

Clinical heterogeneity of autosomal recessive spastic paraplegias: analysis of 106 patients in 46 families.Semantic proximity Read ↗

A new locus (SPG47) maps to 1p13.2-1p12 in an Arabic family with complicated autosomal recessive hereditary spastic paraplegia and thin corpus callosum.Semantic proximity Read ↗

A novel locus for an autosomal recessive hereditary spastic paraplegia (SPG35) maps to 16q21-q23.Semantic proximity Read ↗

A new locus for autosomal dominant pure spastic paraplegia, on chromosome 2q24-q34.Semantic proximity Read ↗

Autosomal dominant spastic paraplegia with peripheral neuropathy maps to chr12q23-24.Semantic proximity Read ↗

A new locus (SPG46) maps to 9p21.2-q21.12 in a Tunisian family with a complicated autosomal recessive hereditary spastic paraplegia with mental impairment and thin corpus callosum.Semantic proximity Read ↗

A novel locus for pure recessive hereditary spastic paraplegia maps to 10q22.1-10q24.1.Semantic proximity Read ↗

Autosomal recessive spastic paraplegia (SPG45) with mental retardation maps to 10q24.3-q25.1.Semantic proximity Read ↗

Clinical and genetic aspects of hereditary spastic paraplegia in patients from Turkey.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.