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Article

Autosomal recessive spastic paraplegia (SPG45) with mental retardation maps to 10q24.3-q25.1.

Neurogenetics - 1 Oct 2009

Dursun Umut, Koroglu Cigdem, Kocasoy Orhan Elif, Ugur Sibel Aylin, Tolun Aslihan

Abstract excerpt

Hereditary spastic paraplegias (HSPs) are characterized by progressive spasticity in the lower limbs. They are clinically heterogeneous, and pure forms as well as complicated forms with other accompanying clinical findings are known. HSPs are also genetically heterogeneous. We performed clinical and genetic studies in a consanguineous family with five affected members. A genome scan using 405 microsatellite...

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Source

Identifiers

PMID: 19415352
DOI: 10.1007/s10048-009-0191-3

Genes

MRPL43

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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