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Article

Autosomal dominant spastic paraplegia with peripheral neuropathy maps to chr12q23-24.

Neurology - 2 Jun 2009

Schüle R, Bonin M, Dürr A, Forlani S, Sperfeld A D, Klimpe S, Mueller J C, Seibel A, van de Warrenburg B P, Bauer P, Schöls L

Abstract excerpt

OBJECTIVE: Hereditary spastic paraplegias (HSP) are genetically exceedingly heterogeneous. To date, 37 genetic loci for HSP have been described (SPG1-41), among them 16 loci for autosomal dominant disease. Notwithstanding, further genetic heterogeneity is to be expected in HSP, as various HSP families do not link to any of the known HSP loci. In this study, we aimed to map the disease locus in a German family...

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Share to Chromosomes, Human, Pair 12
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19357379
DOI: 10.1212/WNL.0b013e3181a6086c

Genes

ATXN2
HSPB8
IFT81
VPS29

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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