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Article

Invasive characteristics of apathogenic Shigella flexneri 5a2c mutant obtained under the effect of furazolidone.

Bulletin of experimental biology and medicine - 1 May 2004

Efremova T N, Gruzdeva I G, Matveev I V, Bozhokina E S, Komissarchuk Ya Yu, Fedorova Z F, Khaitlina S Yu

Abstract excerpt

Apathogenic Shigella flexneri 5a2c mutant treated with furazolidone can infect eucaryotic cells. These bacteria contain no virulence genes responsible for Sh. flexneri invasion, which seems to be the cause of their apathogenicity. The capacity of bacteria to penetrate into eucaryotic cells correlates with the appearance of ECP 32 protease specifically cleaving actin.

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Identifiers

PMID: 15455123
DOI: 10.1023/b:bebm.0000038158.27725.41

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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