Article
Peripheral blood hematopoietic progenitor/stem cells proliferate to form colonies in liquid culture but require contact with vascular endothelial cells and GM-CSF.
International journal of cell cloning - 1 Mar 1992
Monroy R L, Davis T A, Nielsen T B, Staton A J
Abstract excerpt
To test the hypothesis whether peripheral blood hematopoietic progenitor/stem cells (PBSCs) interact with vascular endothelial cells during events leading to extramedullary hematopoiesis, we cocultured T-cell depleted, peripheral blood mononuclear cells obtained from cytokine treated primates in...
Topics
- Animals
- Blood Component Removal
- Cell Communication
- Cell Division
- Cells, Cultured
- Colony-Forming Units Assay
- Endothelium, Vascular
- Granulocyte-Macrophage Colony-Stimulating Factor
- Hematopoietic Stem Cells
- Interleukin-1
- Interleukin-3
- Macaca mulatta
- Phenotype
- Recombinant Proteins
- Swine