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Article

The presence of activated CD4(+) T cells is essential for the formation of colony-forming unit-endothelial cells by CD14(+) cells.

Journal of immunology (Baltimore, Md. : 1950) - 1 Apr 2008

van Beem Rachel T, Noort Willy A, Voermans Carlijn, Kleijer Marion, ten Brinke Anja, van Ham S Marieke, van der Schoot C Ellen, Zwaginga Jaap Jan

Abstract excerpt

The number of colony forming unit-endothelial cells (CFU-EC) in human peripheral blood was found to be a biological marker for several vascular diseases. In this study, the heterogeneous composition of immune cells in the CFU-ECs was investigated. We confirmed that monocytes are essential for the formation of CFU-ECs. Also, however, CD4(+) T cells were found to be indispensable for the induction of CFU-EC...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18354240
DOI: 10.4049/jimmunol.180.7.5141

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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