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Article

Endothelial cell support of hematopoiesis is differentially altered by IL-1 and glucocorticoids.

Leukemia - 1 Aug 1998

Jazwiec B, Solanilla A, Grosset C, Mahon F X, Dupouy M, Pigeonnier-Lagarde V, Belloc F, Schweitzer K, Reiffers J, Ripoche J

Abstract excerpt

We investigated the ability of endothelial cells (EC) to support hematopoiesis in contact and non-contact cocultures with isolated CD34+ or CD34/CD38low cells. In the absence of exogenous cytokines, umbilical vein EC (HUVEC) efficiently support proliferation of hematopoietic cells and generation of colony-forming cells (CFC). Cytokines (IL-6, LIF, G-CSF, GM-CSF, M-CSF, but not IL-1, IL-3, IL-7) were detected in...

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Source

Identifiers

PMID: 9697875
DOI: 10.1038/sj.leu.2401086

Genes

LIF
TPO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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