Article
Redefining endothelial progenitor cells via clonal analysis and hematopoietic stem/progenitor cell principals.
Blood - 1 Mar 2007
Yoder Mervin C, Mead Laura E, Prater Daniel, Krier Theresa R, Mroueh Karim N, Li Fang, Krasich Rachel, Temm Constance J, Prchal Josef T, Ingram David A
Abstract excerpt
The limited vessel-forming capacity of infused endothelial progenitor cells (EPCs) into patients with cardiovascular dysfunction may be related to a misunderstanding of the biologic potential of the cells. EPCs are generally identified by cell surface antigen expression or counting in a commercially available kit that identifies "endothelial cell colony-forming units" (CFU-ECs). However, the origin, proliferative...
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