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Article

Spontaneous multiple mutations show both proximal spacing consistent with chronocoordinate events and alterations with p53-deficiency.

Mutation research - 4 Oct 2004

Hill Kathleen A, Wang Jicheng, Farwell Kelly D, Scaringe William A, Sommer Steve S

Abstract excerpt

Analysis of spontaneous multiple mutations in normal and tumor cells may constrain hypotheses about the mechanisms responsible for multiple mutations and provide insight into the mutator phenotype. In a previous study, spontaneous doublets in Big Blue mice were dramatically more frequent than exp...

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Identifiers

PMID: 15450421
DOI: 10.1016/j.mrfmmm.2004.05.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15450421-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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