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Article

O-linked fucose is present in the first epidermal growth factor domain of factor XII but not protein C.

1 Mar 1992

Abstract excerpt

Epidermal growth factor (EGF) domains are found in many proteins, particularly those of the coagulation/fibrinolytic system. We and others have demonstrated that tissue plasminogen activator (t-PA) and prourokinase are modified by the attachment of fucose to equivalent threonine residues within their EGF domains. Factor XII and protein C each contain two EGF domains; in both proteins, the EGF domain nearest the N...

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Identifiers

PMID: 1544894
DOI: 10.1016/s0021-9258(18)42736-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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O-linked fucose is present in the first epidermal growth factor domain of factor XII but not protein C.PMID 1544894Read ↗

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Glycosylation of two recombinant human uterine tissue plasminogen activator variants carrying an additional N-glycosylation site in the epidermal-growth-factor-like domain.Semantic proximity Read ↗

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Importance of the hinge region between alpha-helix F and the main part of serpins, based upon identification of the epitope of plasminogen activator inhibitor type 1 neutralizing antibodies.Semantic proximity Read ↗

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An A alpha Ser-434 to N-glycosylated Asn substitution in a dysfibrinogen, fibrinogen Caracas II, characterized by impaired fibrin gel formation.Semantic proximity Read ↗

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